Cargando…

JAK2 inhibitor CEP-33779 prevents mouse oocyte maturation in vitro

The inhibitor CEP-33779 is a specific selective inhibitor of Janus kinase 2 (JAK2). In most somatic cells, JAK2 plays essential roles in cellular signal transduction and in the regulation of cell cycle. Little is known regarding the effects of JAK2 on mammalian oocyte maturation. In the present stud...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Changli, Li, Rong, Luo, Haibing, Xu, Mingfeng, Zhang, Xiujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518536/
https://www.ncbi.nlm.nih.gov/pubmed/28615348
http://dx.doi.org/10.1042/BSR20170642