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Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders

OBJECTIVE: Brown and white adipose tissue exerts pleiotropic effects on systemic energy metabolism in part by releasing endocrine factors. Neuregulin 4 (Nrg4) was recently identified as a brown fat-enriched secreted factor that ameliorates diet-induced metabolic disorders, including insulin resistan...

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Detalles Bibliográficos
Autores principales: Chen, Zhimin, Wang, Guo-Xiao, Ma, Sara L., Jung, Dae Young, Ha, Hyekyung, Altamimi, Tariq, Zhao, Xu-Yun, Guo, Liang, Zhang, Peng, Hu, Chun-Rui, Cheng, Ji-Xin, Lopaschuk, Gary D., Kim, Jason K., Lin, Jiandie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518721/
https://www.ncbi.nlm.nih.gov/pubmed/28752050
http://dx.doi.org/10.1016/j.molmet.2017.03.016