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Dietary sugars, not lipids, drive hypothalamic inflammation

OBJECTIVE: The hypothalamus of hypercaloric diet-induced obese animals is featured by a significant increase of microglial reactivity and its associated cytokine production. However, the role of dietary components, in particular fat and carbohydrate, with respect to the hypothalamic inflammatory res...

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Detalles Bibliográficos
Autores principales: Gao, Yuanqing, Bielohuby, Maximilian, Fleming, Thomas, Grabner, Gernot F., Foppen, Ewout, Bernhard, Wagner, Guzmán-Ruiz, Mara, Layritz, Clarita, Legutko, Beata, Zinser, Erwin, García-Cáceres, Cristina, Buijs, Ruud M., Woods, Stephen C., Kalsbeek, Andries, Seeley, Randy J., Nawroth, Peter P., Bidlingmaier, Martin, Tschöp, Matthias H., Yi, Chun-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518723/
https://www.ncbi.nlm.nih.gov/pubmed/28752053
http://dx.doi.org/10.1016/j.molmet.2017.06.008