Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE(−/−) mouse model of atherosclerosis with alterations in IL10/AMPKα pathway

OBJECTIVE: Cardiovascular disease (CVD) is the most prevalent cause of mortality among patients with Type 1 or Type 2 diabetes, due to accelerated atherosclerosis. Recent evidence suggests a strong link between atherosclerosis and insulin resistance due to impaired insulin receptor (IR) signaling. M...

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Detalles Bibliográficos
Autores principales: Thompson, D., Morrice, N., Grant, L., Le Sommer, S., Ziegler, K., Whitfield, P., Mody, N., Wilson, H.M., Delibegović, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518727/
https://www.ncbi.nlm.nih.gov/pubmed/28752048
http://dx.doi.org/10.1016/j.molmet.2017.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518727/
https://www.ncbi.nlm.nih.gov/pubmed/28752048
http://dx.doi.org/10.1016/j.molmet.2017.06.003

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