Identification of a CD4 T-cell epitope in the hemagglutinin stalk domain of pandemic H1N1 influenza virus and its antigen-driven TCR usage signature in BALB/c mice

The stalk region of the influenza virus hemagglutinin is relatively well conserved compared with the globular head domain, which makes it a potential target for use as a universal vaccine against influenza. However, the role of CD4 T cells in the hemagglutinin stalk-specific immune response is not c...

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Detalles Bibliográficos
Autores principales: Lu, I-Na, Farinelle, Sophie, Sausy, Aurélie, Muller, Claude P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518815/
https://www.ncbi.nlm.nih.gov/pubmed/27157498
http://dx.doi.org/10.1038/cmi.2016.20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518815/
https://www.ncbi.nlm.nih.gov/pubmed/27157498
http://dx.doi.org/10.1038/cmi.2016.20

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