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Human CD39(hi) regulatory T cells present stronger stability and function under inflammatory conditions

Autoimmune diseases are characterized by an imbalance between regulatory T cells and effector T-cell subsets, such as Th1 and Th17 cells. Studies have confirmed that natural CD4(+)Foxp3(+) Tregs were unstable and dysfunctional in the presence of pro-inflammatory cytokines. In the current study, huma...

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Detalles Bibliográficos
Autores principales: Gu, Jian, Ni, Xuhao, Pan, Xiongxiong, Lu, Hao, Lu, Yunjie, Zhao, Jie, Guo Zheng, Song, Hippen, Keli L, Wang, Xuehao, Lu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518817/
https://www.ncbi.nlm.nih.gov/pubmed/27374793
http://dx.doi.org/10.1038/cmi.2016.30