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Human CD39(hi) regulatory T cells present stronger stability and function under inflammatory conditions
Autoimmune diseases are characterized by an imbalance between regulatory T cells and effector T-cell subsets, such as Th1 and Th17 cells. Studies have confirmed that natural CD4(+)Foxp3(+) Tregs were unstable and dysfunctional in the presence of pro-inflammatory cytokines. In the current study, huma...
Autores principales: | Gu, Jian, Ni, Xuhao, Pan, Xiongxiong, Lu, Hao, Lu, Yunjie, Zhao, Jie, Guo Zheng, Song, Hippen, Keli L, Wang, Xuehao, Lu, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518817/ https://www.ncbi.nlm.nih.gov/pubmed/27374793 http://dx.doi.org/10.1038/cmi.2016.30 |
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