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Statin use, candidate mevalonate pathway biomarkers, and colon cancer survival in a population-based cohort study

BACKGROUND: Statin use after colorectal cancer diagnosis may improve survival but evidence from observational studies is conflicting. The anti-cancer effect of statins may be restricted to certain molecular subgroups. In this population-based cohort study, the interaction between p53 and 3-hydroxy-3...

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Detalles Bibliográficos
Autores principales: Gray, Ronan T, Loughrey, Maurice B, Bankhead, Peter, Cardwell, Chris R, McQuaid, Stephen, O'Neill, Roisin F, Arthur, Kenneth, Bingham, Victoria, McGready, Claire, Gavin, Anna T, James, Jacqueline A, Hamilton, Peter W, Salto-Tellez, Manuel, Murray, Liam J, Coleman, Helen G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518863/
https://www.ncbi.nlm.nih.gov/pubmed/28524155
http://dx.doi.org/10.1038/bjc.2017.139