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Statin use, candidate mevalonate pathway biomarkers, and colon cancer survival in a population-based cohort study
BACKGROUND: Statin use after colorectal cancer diagnosis may improve survival but evidence from observational studies is conflicting. The anti-cancer effect of statins may be restricted to certain molecular subgroups. In this population-based cohort study, the interaction between p53 and 3-hydroxy-3...
Autores principales: | Gray, Ronan T, Loughrey, Maurice B, Bankhead, Peter, Cardwell, Chris R, McQuaid, Stephen, O'Neill, Roisin F, Arthur, Kenneth, Bingham, Victoria, McGready, Claire, Gavin, Anna T, James, Jacqueline A, Hamilton, Peter W, Salto-Tellez, Manuel, Murray, Liam J, Coleman, Helen G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518863/ https://www.ncbi.nlm.nih.gov/pubmed/28524155 http://dx.doi.org/10.1038/bjc.2017.139 |
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