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Molecular assembly of rhodopsin with G protein-coupled receptor kinases

G protein-coupled receptor kinases (GRKs) play pivotal roles in desensitizing GPCR signaling but little is known about how GRKs recognize and phosphorylate GPCRs due to the technical difficulties in detecting the highly dynamic GPCR/GRK interaction. By combining a genetic approach with multiple bioc...

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Detalles Bibliográficos
Autores principales: He, Yuanzheng, Gao, Xiang, Goswami, Devrishi, Hou, Li, Pal, Kuntal, Yin, Yanting, Zhao, Gongpu, Ernst, Oliver P, Griffin, Patrick, Melcher, Karsten, Xu, H Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518878/
https://www.ncbi.nlm.nih.gov/pubmed/28524165
http://dx.doi.org/10.1038/cr.2017.72