Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations

A functioning gene drive system could fundamentally change our strategies for the control of vector-borne diseases by facilitating rapid dissemination of transgenes that prevent pathogen transmission or reduce vector capacity. CRISPR/Cas9 gene drive promises such a mechanism, which works by converti...

Descripción completa

Detalles Bibliográficos
Autores principales: Champer, Jackson, Reeves, Riona, Oh, Suh Yeon, Liu, Chen, Liu, Jingxian, Clark, Andrew G., Messer, Philipp W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518997/
https://www.ncbi.nlm.nih.gov/pubmed/28727785
http://dx.doi.org/10.1371/journal.pgen.1006796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518997/
https://www.ncbi.nlm.nih.gov/pubmed/28727785
http://dx.doi.org/10.1371/journal.pgen.1006796

Ejemplares similares