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Manganese transporter Slc39a14 deficiency revealed its key role in maintaining manganese homeostasis in mice

SLC39A14 (also known as ZIP14), a member of the SLC39A transmembrane metal transporter family, has been reported to mediate the cellular uptake of iron and zinc. Recently, however, mutations in the SLC39A14 gene have been linked to manganese (Mn) accumulation in the brain and childhood-onset parkins...

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Detalles Bibliográficos
Autores principales: Xin, Yongjuan, Gao, Hong, Wang, Jia, Qiang, Yuzhen, Imam, Mustapha Umar, Li, Yang, Wang, Jianyao, Zhang, Ruochen, Zhang, Huizhen, Yu, Yingying, Wang, Hao, Luo, Haiyang, Shi, Changhe, Xu, Yuming, Hojyo, Shintaro, Fukada, Toshiyuki, Min, Junxia, Wang, Fudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519003/
https://www.ncbi.nlm.nih.gov/pubmed/28751976
http://dx.doi.org/10.1038/celldisc.2017.25