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Coupling killing to neutralization: combined therapy with ceftriaxone/Pep19-2.5 counteracts sepsis in rabbits

Sepsis, which is induced by severe bacterial infections, is a major cause of death worldwide, and therapies combating the disease are urgently needed. Because many drugs have failed in clinical trials despite their efficacy in mouse models, the development of reliable animal models of sepsis is in g...

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Detalles Bibliográficos
Autores principales: Bárcena-Varela, Sergio, Martínez-de-Tejada, Guillermo, Martin, Lukas, Schuerholz, Tobias, Gil-Royo, Ana Gloria, Fukuoka, Satoshi, Goldmann, Torsten, Droemann, Daniel, Correa, Wilmar, Gutsmann, Thomas, Brandenburg, Klaus, Heinbockel, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519016/
https://www.ncbi.nlm.nih.gov/pubmed/28620220
http://dx.doi.org/10.1038/emm.2017.75