Cargando…

Lineage conversion of mouse fibroblasts to pancreatic α-cells

α-cells, which synthesize glucagon, also support β-cell survival and have the capacity to transdifferentiate into β-cells. However, the role of α-cells in pathological conditions and their putative clinical applications remain elusive due in large part to the lack of mature α-cells. Here, we present...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Tianjin, Sun, Liangliang, Jiang, Beige, Li, Limei, Cen, Jin, Chen, Xiaotao, Zhang, Zhaoyun, Wang, Qinghua, Cheng, Xin, Shi, Yongquan, Hui, Lijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519020/
https://www.ncbi.nlm.nih.gov/pubmed/28665920
http://dx.doi.org/10.1038/emm.2017.84