The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer

The receptor tyrosine kinases (RTKs) TYRO3, AXL and MERTK (TAM) have well-described oncogenic functions in a number of cancers. Notwithstanding, TAM RTKs are also potent and indispensable inhibitors of inflammation. The combined deletion of Axl and Mertk in mice enhances chronic inflammation and aut...

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Detalles Bibliográficos
Autores principales: Uribe, Diana J., Mandell, Edward K., Watson, Adam, Martinez, Jesse D., Leighton, Jonathan A., Ghosh, Sourav, Rothlin, Carla V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519024/
https://www.ncbi.nlm.nih.gov/pubmed/28727830
http://dx.doi.org/10.1371/journal.pone.0179979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519024/
https://www.ncbi.nlm.nih.gov/pubmed/28727830
http://dx.doi.org/10.1371/journal.pone.0179979

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