An NS5A single optimized method to determine genotype, subtype and resistance profiles of Hepatitis C strains

The objective was to develop a method of HCV genome sequencing that allowed simultaneous genotyping and NS5A inhibitor resistance profiling. In order to validate the use of a unique RT-PCR for genotypes 1–5, 142 plasma samples from patients infected with HCV were analysed. The NS4B-NS5A partial regi...

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Detalles Bibliográficos
Autores principales: Andre-Garnier, Elisabeth, Besse, Bernard, Rodallec, Audrey, Ribeyrol, Olivier, Ferre, Virginie, Luco, Caroline, Le Guen, Laura, Bourgeois, Nathalie, Gournay, Jérôme, Billaud, Eric, Raffi, François, Coste-Burel, Marianne, Imbert-Marcille, Berthe-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519038/
https://www.ncbi.nlm.nih.gov/pubmed/28727784
http://dx.doi.org/10.1371/journal.pone.0179562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519038/
https://www.ncbi.nlm.nih.gov/pubmed/28727784
http://dx.doi.org/10.1371/journal.pone.0179562

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