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Low PCSK9 levels are correlated with mortality in patients with end-stage liver disease

INTRODUCTION: Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a key role in the cholesterol metabolism and is synthesized by the liver. It interacts with the LDL-receptor to promote its degradation. The model of end-stage liver disease (MELD) score is a well-established tool to estimate...

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Detalles Bibliográficos
Autores principales: Schlegel, Valentin, Treuner-Kaueroff, Theresa, Seehofer, Daniel, Berg, Thomas, Becker, Susen, Ceglarek, Uta, Thiery, Joachim, Kaiser, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519179/
https://www.ncbi.nlm.nih.gov/pubmed/28727814
http://dx.doi.org/10.1371/journal.pone.0181540