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Atomistic modeling of alternating access of a mitochondrial ADP/ATP membrane transporter with molecular simulations
The mitochondrial ADP/ATP carrier (AAC) is a membrane transporter that exchanges a cytosolic ADP for a matrix ATP. Atomic structures in an outward-facing (OF) form which binds an ADP from the intermembrane space have been solved by X-ray crystallography, and revealed their unique pseudo three-fold s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519185/ https://www.ncbi.nlm.nih.gov/pubmed/28727843 http://dx.doi.org/10.1371/journal.pone.0181489 |