A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling

Here, by combining lipidomics with transcriptome analysis, we demonstrate that Rb depletion in mouse embryonic fibroblastss induces significant alterations in their lipid composition. We discovered that Rb depletion induced increase in lysophosphatidylserine, diacylglycerol (DAG), fatty acid (FA), a...

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Detalles Bibliográficos
Autores principales: Muranaka, H, Hayashi, A, Minami, K, Kitajima, S, Kohno, S, Nishimoto, Y, Nagatani, N, Suzuki, M, Kulathunga, L A N, Sasaki, N, Okada, N, Matsuzaka, T, Shimano, H, Tada, H, Takahashi, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519198/
https://www.ncbi.nlm.nih.gov/pubmed/28650445
http://dx.doi.org/10.1038/oncsis.2017.51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519198/
https://www.ncbi.nlm.nih.gov/pubmed/28650445
http://dx.doi.org/10.1038/oncsis.2017.51

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