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8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle

Oxidative stress resulting from endogenous and exogenous sources causes damage to cellular components, including genomic and mitochondrial DNA. Oxidative DNA damage is primarily repaired via the base excision repair pathway that is initiated by DNA glycosylases. 8-oxoguanine DNA glycosylase (OGG1) r...

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Detalles Bibliográficos
Autores principales: Vartanian, Vladimir, Tumova, Jana, Dobrzyn, Pawel, Dobrzyn, Agnieszka, Nakabeppu, Yusaku, Lloyd, R. Stephen, Sampath, Harini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519207/
https://www.ncbi.nlm.nih.gov/pubmed/28727777
http://dx.doi.org/10.1371/journal.pone.0181687