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8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle
Oxidative stress resulting from endogenous and exogenous sources causes damage to cellular components, including genomic and mitochondrial DNA. Oxidative DNA damage is primarily repaired via the base excision repair pathway that is initiated by DNA glycosylases. 8-oxoguanine DNA glycosylase (OGG1) r...
Autores principales: | Vartanian, Vladimir, Tumova, Jana, Dobrzyn, Pawel, Dobrzyn, Agnieszka, Nakabeppu, Yusaku, Lloyd, R. Stephen, Sampath, Harini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519207/ https://www.ncbi.nlm.nih.gov/pubmed/28727777 http://dx.doi.org/10.1371/journal.pone.0181687 |
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