Functional and phylogenetic evidence of a bacterial origin for the first enzyme in sphingolipid biosynthesis in a phylum of eukaryotic protozoan parasites

Toxoplasma gondii is an obligate, intracellular eukaryotic apicomplexan protozoan parasite that can cause fetal damage and abortion in both animals and humans. Sphingolipids are essential and ubiquitous components of eukaryotic membranes that are both synthesized and scavenged by the Apicomplexa. He...

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Detalles Bibliográficos
Autores principales: Mina, John G., Thye, Julie K., Alqaisi, Amjed Q. I., Bird, Louise E., Dods, Robert H., Grøftehauge, Morten K., Mosely, Jackie A., Pratt, Steven, Shams-Eldin, Hosam, Schwarz, Ralph T., Pohl, Ehmke, Denny, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519370/
https://www.ncbi.nlm.nih.gov/pubmed/28578314
http://dx.doi.org/10.1074/jbc.M117.792374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519370/
https://www.ncbi.nlm.nih.gov/pubmed/28578314
http://dx.doi.org/10.1074/jbc.M117.792374

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