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Randomized Trial Comparing Esomeprazole and Rabeprazole in First-line Eradication Therapy for Helicobacter pylori Infection based on the Serum Levels of Pepsinogens

OBJECTIVE: CYP2C19 metabolic activity influences the efficacy of Helicobacter pylori eradication therapies comprising PPIs. Rabeprazole (RPZ) and esomeprazole (EPZ) are PPIs not extensively metabolized by CYP2C19. The aim of this study was to elucidate whether or not first-line triple therapies usin...

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Detalles Bibliográficos
Autores principales: Shimoyama, Tadashi, Chinda, Daisuke, Sawada, Yoshihiko, Komai, Kazuo, Chiba, Hironobu, Saito, Yoshiharu, Sasaki, Yoshio, Matsuzaka, Masashi, Fukuda, Shinsaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519461/
https://www.ncbi.nlm.nih.gov/pubmed/28674348
http://dx.doi.org/10.2169/internalmedicine.56.7823