Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole

CYP3A4-inhibitors can potentiate the hypotensive effect of calcium-channel blockers. However, insufficient attention to such drug interactions may result in serious adverse reactions. A 71-year-old hypertensive man prescribed nifedipine was hospitalized for infectious endophthalmitis. Antimicrobial...

Descripción completa

Detalles Bibliográficos
Autores principales: Mishima, Eikan, Maruyama, Kazuichi, Nakazawa, Toru, Abe, Takaaki, Ito, Sadayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519471/
https://www.ncbi.nlm.nih.gov/pubmed/28674358
http://dx.doi.org/10.2169/internalmedicine.56.8313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519471/
https://www.ncbi.nlm.nih.gov/pubmed/28674358
http://dx.doi.org/10.2169/internalmedicine.56.8313

Ejemplares similares