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Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole

CYP3A4-inhibitors can potentiate the hypotensive effect of calcium-channel blockers. However, insufficient attention to such drug interactions may result in serious adverse reactions. A 71-year-old hypertensive man prescribed nifedipine was hospitalized for infectious endophthalmitis. Antimicrobial...

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Detalles Bibliográficos
Autores principales:	Mishima, Eikan, Maruyama, Kazuichi, Nakazawa, Toru, Abe, Takaaki, Ito, Sadayoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Internal Medicine 2017
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519471/ https://www.ncbi.nlm.nih.gov/pubmed/28674358 http://dx.doi.org/10.2169/internalmedicine.56.8313

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