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Activating Transcription Factor-5 Knockdown Reduces Aggressiveness of Mammary Tumor Cells and Attenuates Mammary Tumor Growth

Activating transcription factor-5 (ATF5) is an anti-apoptotic factor and has been implicated in enhancing the survival of cancer cells under stress and in regulating the autophagy process. Targeting ATF5 in anticancer therapy may be particularly attractive because of its differential role in cancer...

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Detalles Bibliográficos
Autores principales: Ben-Shmuel, Sarit, Rashed, Rola, Rostoker, Ran, Isakov, Elina, Shen-Orr, Zila, LeRoith, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519529/
https://www.ncbi.nlm.nih.gov/pubmed/28785242
http://dx.doi.org/10.3389/fendo.2017.00173