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PLD1 promotes dendritic spine development by inhibiting ADAM10-mediated N-cadherin cleavage

Synapses are the basic units of information transmission, processing and integration in the nervous system. Dysfunction of the synaptic development has been recognized as one of the main reasons for mental dementia and psychiatric diseases such as Alzheimer’s disease and autism. However, the underly...

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Detalles Bibliográficos
Autores principales: Luo, Li-Da, Li, Gang, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519554/
https://www.ncbi.nlm.nih.gov/pubmed/28729535
http://dx.doi.org/10.1038/s41598-017-06121-2