Anti-Tumor Activity and Immunotherapeutic Potential of a Bisphosphonate Prodrug

Bisphosphonates have benefits in breast cancer and multiple myeloma patients and have been used with adoptive immunotherapy with γδ T cells expressing Vγ2 Vδ2 TCRs. Although treatment with γδ T cells is safe, it has shown limited efficacy. Present bisphosphonates stimulate γδ T cells but were design...

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Detalles Bibliográficos
Autores principales: Tanaka, Yoshimasa, Iwasaki, Masashi, Murata-Hirai, Kaoru, Matsumoto, Kenji, Hayashi, Kosuke, Okamura, Haruki, Sugie, Tomoharu, Minato, Nagahiro, Morita, Craig T., Toi, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519590/
https://www.ncbi.nlm.nih.gov/pubmed/28729550
http://dx.doi.org/10.1038/s41598-017-05553-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519590/
https://www.ncbi.nlm.nih.gov/pubmed/28729550
http://dx.doi.org/10.1038/s41598-017-05553-0

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