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PTEN/FOXO3/AKT pathway regulates cell death and mediates morphogenetic differentiation of Colorectal Cancer Cells under Simulated Microgravity

Gravity is a major physical factor determining the stress and strain around cells. Both in space experiments and ground simulation, change in gravity impacts the viability and function of various types of cells as well as in vivo conditions. Cancer cells have been shown to die under microgravity. Th...

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Detalles Bibliográficos
Autores principales: Arun, Raj Pranap, Sivanesan, Divya, Vidyasekar, Prasanna, Verma, Rama Shanker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519599/
https://www.ncbi.nlm.nih.gov/pubmed/28729699
http://dx.doi.org/10.1038/s41598-017-06416-4