A comparative strategy for single-nucleus and single-cell transcriptomes confirms accuracy in predicted cell-type expression from nuclear RNA

Significant heterogeneities in gene expression among individual cells are typically interrogated using single whole cell approaches. However, tissues that have highly interconnected processes, such as in the brain, present unique challenges. Single-nucleus RNA sequencing (SNS) has emerged as an alte...

Descripción completa

Detalles Bibliográficos
Autores principales: Lake, Blue B., Codeluppi, Simone, Yung, Yun C., Gao, Derek, Chun, Jerold, Kharchenko, Peter V., Linnarsson, Sten, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519641/
https://www.ncbi.nlm.nih.gov/pubmed/28729663
http://dx.doi.org/10.1038/s41598-017-04426-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519641/
https://www.ncbi.nlm.nih.gov/pubmed/28729663
http://dx.doi.org/10.1038/s41598-017-04426-w

Ejemplares similares