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Further optimization of peptide substrate enhanced assay performance for BoNT/A detection by MALDI-TOF mass spectrometry

Rapid and sensitive detection of botulinum neurotoxins (BoNTs), which cause botulism, is essential in a public health emergency or bioterrorism event. We have previously developed a mass spectrometry (MS)-based functional method, Endopep-MS assay, for the fast detection and differentiation of all Bo...

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Detalles Bibliográficos
Autores principales: Wang, Dongxia, Baudys, Jakub, Hoyt, Kaitlin M., Barr, John R., Kalb, Suzanne R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519644/
https://www.ncbi.nlm.nih.gov/pubmed/28573317
http://dx.doi.org/10.1007/s00216-017-0421-8