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In vitro and in vivo pharmacokinetics and metabolism of synthetic cannabinoids CUMYL-PICA and 5F-CUMYL-PICA

CUMYL-PICA [1-pentyl-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide] and 5F-CUMYL-PICA [1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide] are recently identified recreationally used/abused synthetic cannabinoids, but have uncharacterized pharmacokinetic profiles and metabolic proc...

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Detalles Bibliográficos
Autores principales: Kevin, Richard C., Lefever, Timothy W., Snyder, Rodney W., Patel, Purvi R., Fennell, Timothy R., Wiley, Jenny L., McGregor, Iain S., Thomas, Brian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519669/
https://www.ncbi.nlm.nih.gov/pubmed/28824730
http://dx.doi.org/10.1007/s11419-017-0361-1