Cargando…
In vitro and in vivo pharmacokinetics and metabolism of synthetic cannabinoids CUMYL-PICA and 5F-CUMYL-PICA
CUMYL-PICA [1-pentyl-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide] and 5F-CUMYL-PICA [1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide] are recently identified recreationally used/abused synthetic cannabinoids, but have uncharacterized pharmacokinetic profiles and metabolic proc...
Autores principales: | Kevin, Richard C., Lefever, Timothy W., Snyder, Rodney W., Patel, Purvi R., Fennell, Timothy R., Wiley, Jenny L., McGregor, Iain S., Thomas, Brian F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519669/ https://www.ncbi.nlm.nih.gov/pubmed/28824730 http://dx.doi.org/10.1007/s11419-017-0361-1 |
Ejemplares similares
-
CUMYL-4CN-BINACA Is an Efficacious and Potent Pro-Convulsant Synthetic Cannabinoid Receptor Agonist
por: Kevin, Richard C., et al.
Publicado: (2019) -
Human phase I metabolism of the novel synthetic cannabinoid 5F-CUMYL-PEGACLONE
por: Mogler, Lukas, et al.
Publicado: (2018) -
5F-Cumyl-PINACA in ‘e-liquids’ for electronic cigarettes: comprehensive characterization of a new type of synthetic cannabinoid in a trendy product including investigations on the in vitro and in vivo phase I metabolism of 5F-Cumyl-PINACA and its non-fluorinated analog Cumyl-PINACA
por: Angerer, Verena, et al.
Publicado: (2018) -
Off-target pharmacological profiling of synthetic cannabinoid receptor agonists including AMB-FUBINACA, CUMYL-PINACA, PB-22, and XLR-11
por: Kevin, Richard C., et al.
Publicado: (2022) -
Phase I In Vitro Metabolic Profiling of the Synthetic Cannabinoid Receptor Agonists CUMYL-THPINACA and ADAMANTYL-THPINACA
por: Monti, Manuela Carla, et al.
Publicado: (2021)