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Sudan ebolavirus long recovered survivors produce GP-specific Abs that are of the IgG1 subclass and preferentially bind FcγRI

Ebolavirus is a highly lethal pathogen, causing a severe hemorrhagic disease with a high fatality rate. To better understand immune correlates of protection by virus specific IgG, we investigated the evolution of the Fcγ receptors (FcγRs)-activating capabilities of antiviral IgG in serum samples of...

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Detalles Bibliográficos
Autores principales: Radinsky, Olga, Edri, Avishay, Brusilovsky, Michael, Fedida-Metula, Shlomit, Sobarzo, Ariel, Gershoni-Yahalom, Orly, Lutwama, Julius, Dye, John, Lobel, Leslie, Porgador, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519693/
https://www.ncbi.nlm.nih.gov/pubmed/28729706
http://dx.doi.org/10.1038/s41598-017-06226-8