Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization

HIV-1 Nef is an important pathogenic factor for HIV/AIDS pathogenesis. Studies have shown that the association of Nef with the inner leaflet of the plasma membrane and with endocytic and perinuclear vesicles is essential for most activities of Nef. Using purified recombinant proteins in pull-down as...

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Detalles Bibliográficos
Autores principales: Boeske, Alexandra, Schwarten, Melanie, Ma, Peixiang, Tusche, Markus, Mötter, Jessica, Möller, Christina, Neudecker, Philipp, Hoffmann, Silke, Willbold, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519724/
https://www.ncbi.nlm.nih.gov/pubmed/28729737
http://dx.doi.org/10.1038/s41598-017-06319-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519724/
https://www.ncbi.nlm.nih.gov/pubmed/28729737
http://dx.doi.org/10.1038/s41598-017-06319-4

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