Functional variation of SHP-2 promoter is associated with preterm birth and delayed myelination and motor development in preterm infants

Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP-2) is a cytoplasmic tyrosine phosphatase that is highly expressed in hematopoietic cells and in the CNS and exerts opposite effects on signal transduction by exerting a neuroprotective or proapoptotic effect. Several mutations of S...

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Detalles Bibliográficos
Autores principales: Shim, So-Yeon, Jeong, Hye Jin, Park, Hyo Jin, Kwon, Eun Young, Kim, Bo Min, Choi, Yang Ji, Choi, Youn-Hee, Cho, Su Jin, Choi, Ji Ha, Park, Eun Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519743/
https://www.ncbi.nlm.nih.gov/pubmed/28729690
http://dx.doi.org/10.1038/s41598-017-06401-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519743/
https://www.ncbi.nlm.nih.gov/pubmed/28729690
http://dx.doi.org/10.1038/s41598-017-06401-x

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