Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family

We introduce LytU, a short member of the lysostaphin family of zinc-dependent pentaglycine endopeptidases. It is a potential antimicrobial agent for S. aureus infections and its gene transcription is highly upregulated upon antibiotic treatments along with other genes involved in cell wall synthesis...

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Detalles Bibliográficos
Autores principales: Raulinaitis, Vytas, Tossavainen, Helena, Aitio, Olli, Juuti, Jarmo T., Hiramatsu, Keiichi, Kontinen, Vesa, Permi, Perttu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519744/
https://www.ncbi.nlm.nih.gov/pubmed/28729697
http://dx.doi.org/10.1038/s41598-017-06135-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519744/
https://www.ncbi.nlm.nih.gov/pubmed/28729697
http://dx.doi.org/10.1038/s41598-017-06135-w

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