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Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family
We introduce LytU, a short member of the lysostaphin family of zinc-dependent pentaglycine endopeptidases. It is a potential antimicrobial agent for S. aureus infections and its gene transcription is highly upregulated upon antibiotic treatments along with other genes involved in cell wall synthesis...
Autores principales: | Raulinaitis, Vytas, Tossavainen, Helena, Aitio, Olli, Juuti, Jarmo T., Hiramatsu, Keiichi, Kontinen, Vesa, Permi, Perttu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519744/ https://www.ncbi.nlm.nih.gov/pubmed/28729697 http://dx.doi.org/10.1038/s41598-017-06135-w |
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