Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes

Type 1 diabetes mellitus (T1DM) results from an autoimmune attack against the insulin-producing ß cells which leads to chronic hyperglycemia. Exosomes are lipid vesicles derived from cellular multivesicular bodies that are enriched in specific miRNAs, potentially providing a disease-specific diagnos...

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Detalles Bibliográficos
Autores principales: Garcia-Contreras, Marta, Shah, Sanket H., Tamayo, Alejandro, Robbins, Paul D., Golberg, Ronald B., Mendez, Armando J., Ricordi, Camillo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519761/
https://www.ncbi.nlm.nih.gov/pubmed/28729721
http://dx.doi.org/10.1038/s41598-017-05787-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519761/
https://www.ncbi.nlm.nih.gov/pubmed/28729721
http://dx.doi.org/10.1038/s41598-017-05787-y

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