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Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes
Type 1 diabetes mellitus (T1DM) results from an autoimmune attack against the insulin-producing ß cells which leads to chronic hyperglycemia. Exosomes are lipid vesicles derived from cellular multivesicular bodies that are enriched in specific miRNAs, potentially providing a disease-specific diagnos...
Autores principales: | Garcia-Contreras, Marta, Shah, Sanket H., Tamayo, Alejandro, Robbins, Paul D., Golberg, Ronald B., Mendez, Armando J., Ricordi, Camillo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519761/ https://www.ncbi.nlm.nih.gov/pubmed/28729721 http://dx.doi.org/10.1038/s41598-017-05787-y |
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