Programmed death one homolog maintains the pool size of regulatory T cells by promoting their differentiation and stability

Programmed death one homolog (PD-1H) is an immunoglobulin superfamily molecule and primarily acts as a coinhibitor in the initiation of T cell response to antigens. Here, we report that genetic ablation of PD-1H in mice blocks the differentiation of naive T cells to Foxp3(+) inducible Treg cells (iT...

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Detalles Bibliográficos
Autores principales: Wang, Qi, He, Jianwei, Flies, Dallas B., Luo, Liqun, Chen, Lieping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519767/
https://www.ncbi.nlm.nih.gov/pubmed/28729608
http://dx.doi.org/10.1038/s41598-017-06410-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519767/
https://www.ncbi.nlm.nih.gov/pubmed/28729608
http://dx.doi.org/10.1038/s41598-017-06410-w

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