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Checkpoint inhibitors in the treatment of urological malignancies

Checkpoint inhibitors are monoclonal antibodies attach to several different receptors on T-cells or tumour cells expressing receptors for cytotoxic T-lymphocyte antigen 4 (CTLA-4), programmed death-1 (PD-1) and their ligand (PD-L1). Since 2010, numerous trials on different tumour types have been con...

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Detalles Bibliográficos
Autores principales: Popovic, Lazar S, Matovina-Brko, Gorana, Popovic, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519795/
https://www.ncbi.nlm.nih.gov/pubmed/28761743
http://dx.doi.org/10.1136/esmoopen-2017-000165