Log D versus HPLC derived hydrophobicity: The development of predictive tools to aid in the rational design of bioactive peptoids

Hydrophobicity has proven to be an extremely useful parameter in small molecule drug discovery programmes given that it can be used as a predictive tool to enable rational design. For larger molecules, including peptoids, where folding is possible, the situation is more complicated and the average h...

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Detalles Bibliográficos
Autores principales: Bolt, H. L., Williams, C. E. J., Brooks, R. V., Zuckermann, R. N., Cobb, S. L., Bromley, E. H. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519928/
https://www.ncbi.nlm.nih.gov/pubmed/28085180
http://dx.doi.org/10.1002/bip.23014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519928/
https://www.ncbi.nlm.nih.gov/pubmed/28085180
http://dx.doi.org/10.1002/bip.23014

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