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Log D versus HPLC derived hydrophobicity: The development of predictive tools to aid in the rational design of bioactive peptoids
Hydrophobicity has proven to be an extremely useful parameter in small molecule drug discovery programmes given that it can be used as a predictive tool to enable rational design. For larger molecules, including peptoids, where folding is possible, the situation is more complicated and the average h...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519928/ https://www.ncbi.nlm.nih.gov/pubmed/28085180 http://dx.doi.org/10.1002/bip.23014 |