Continuous Synthesis and Purification by Coupling a Multistep Flow Reaction with Centrifugal Partition Chromatography

Continuous‐flow multistep synthesis is combined with quasi‐continuous final‐product purification to produce pure products from crude reaction mixtures. In the nucleophilic aromatic substitution of 2,4‐difluoronitrobenzene with morpholine followed by a heterogeneous catalytic hydrogenation, the desir...

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Detalles Bibliográficos
Autores principales: Örkényi, Róbert, Éles, János, Faigl, Ferenc, Vincze, Péter, Prechl, Anita, Szakács, Zoltán, Kóti, János, Greiner, István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519935/
https://www.ncbi.nlm.nih.gov/pubmed/28548374
http://dx.doi.org/10.1002/anie.201703852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519935/
https://www.ncbi.nlm.nih.gov/pubmed/28548374
http://dx.doi.org/10.1002/anie.201703852

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