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Target guided synthesis using DNA nano-templates for selectively assembling a G-quadruplex binding c-MYC inhibitor
The development of small molecules is essential to modulate the cellular functions of biological targets in living system. Target Guided Synthesis (TGS) approaches have been used for the identification of potent small molecules for biological targets. We herein demonstrate an innovative example of T...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519986/ https://www.ncbi.nlm.nih.gov/pubmed/28706243 http://dx.doi.org/10.1038/ncomms16103 |