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Target guided synthesis using DNA nano-templates for selectively assembling a G-quadruplex binding c-MYC inhibitor

The development of small molecules is essential to modulate the cellular functions of biological targets in living system. Target Guided Synthesis (TGS) approaches have been used for the identification of potent small molecules for biological targets. We herein demonstrate an innovative example of T...

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Detalles Bibliográficos
Autores principales: Panda, Deepanjan, Saha, Puja, Das, Tania, Dash, Jyotirmayee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519986/
https://www.ncbi.nlm.nih.gov/pubmed/28706243
http://dx.doi.org/10.1038/ncomms16103

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