4-alkyl-L-(Dehydro)proline biosynthesis in actinobacteria involves N-terminal nucleophile-hydrolase activity of γ-glutamyltranspeptidase homolog for C-C bond cleavage

γ-Glutamyltranspeptidases (γ-GTs), ubiquitous in glutathione metabolism for γ-glutamyl transfer/hydrolysis, are N-terminal nucleophile (Ntn)-hydrolase fold proteins that share an autoproteolytic process for self-activation. γ-GT homologues are widely present in Gram-positive actinobacteria where the...

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Detalles Bibliográficos
Autores principales: Zhong, Guannan, Zhao, Qunfei, Zhang, Qinglin, Liu, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519988/
https://www.ncbi.nlm.nih.gov/pubmed/28706296
http://dx.doi.org/10.1038/ncomms16109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519988/
https://www.ncbi.nlm.nih.gov/pubmed/28706296
http://dx.doi.org/10.1038/ncomms16109

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