Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells

Precise spatiotemporal gene regulation is paramount for the establishment and maintenance of cell-specific programmes. Although there is evidence that chromatin neighbourhoods, formed by the zinc-finger protein CTCF, can sequester enhancers and their target genes, there is limited in vivo evidence f...

Descripción completa

Detalles Bibliográficos
Autores principales: Willi, M., Yoo, K. H., Reinisch, F., Kuhns, T. M., Lee, H. K., Wang, C., Hennighausen, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520053/
https://www.ncbi.nlm.nih.gov/pubmed/28714474
http://dx.doi.org/10.1038/ncomms16069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520053/
https://www.ncbi.nlm.nih.gov/pubmed/28714474
http://dx.doi.org/10.1038/ncomms16069

Ejemplares similares