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A comparison of Cox and logistic regression for use in genome-wide association studies of cohort and case-cohort design

Logistic regression is often used instead of Cox regression to analyse genome-wide association studies (GWAS) of single-nucleotide polymorphisms (SNPs) and disease outcomes with cohort and case-cohort designs, as it is less computationally expensive. Although Cox and logistic regression models have...

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Detalles Bibliográficos
Autores principales: Staley, James R, Jones, Edmund, Kaptoge, Stephen, Butterworth, Adam S, Sweeting, Michael J, Wood, Angela M, Howson, Joanna M M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520083/
https://www.ncbi.nlm.nih.gov/pubmed/28594416
http://dx.doi.org/10.1038/ejhg.2017.78